Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.55 |
| ▸ | HTR1A | P08908 | 5/20 | 0.55 |
| ▸ | HTR6 | P50406 | 4/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR5A | P47898 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753134 | 0.77 | HTR7 (0.57) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL9048996 | 0.76 | CYP1A2 (0.68) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL3319555 | 0.75 | HTR7 (0.58) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL4560009 | 0.74 | HRH4 (0.54) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL3759275 | 0.72 | HTR7 (1.00) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL30022433 | 0.72 | HTR7 (1.00) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL18346578 | 0.71 | CSNK1D (0.60) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL14791703 | 0.71 | HTR7 (0.43) | HTR7HTR1AHTR6HTR2AHTR5A | |
| Hydrochloric Acid SCHEMBL1673713 | 0.70 | HTR7 (0.96) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL2403314 | 0.70 | HRH4 (0.47) | HTR7HTR1AHTR6HTR2BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661003-B | alpha-helical analogs with triazine-piperazine backbones and methods of making the same | 株式会社POSCO | 2020-05-19 | — | — | CN | disclosed |
| US-10131650-B2 | Alpha-helix analog having triazine-piperazine backbone and method for preparing same | POSCO (KR) | 2018-11-20 | — | — | US | disclosed |
| US-20170204086-A1 | ALPHA-HELIX ANALOG HAVING TRIAZINE-PIPERAZINE BACKBONE AND METHOD FOR PREPARING SAME | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2017-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204086-A1 | ALPHA-HELIX ANALOG HAVING TRIAZINE-PIPERAZINE BACKBONE AND METHOD FOR PREPARING SAME | HSPH1, HBZ, PITHD1 | HTR7 837/4885HTR1A 1702/4885HTR6 1793/4885 |
| US-10131650-B2 | Alpha-helix analog having triazine-piperazine backbone and method for preparing same | HSPH1, HBZ, PITHD1 | HTR7 837/4885HTR1A 1702/4885HTR6 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.