Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 5/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753134 | 0.77 | HTR7 (0.57) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL18346578 | 0.72 | CSNK1D (0.60) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL19124979 | 0.71 | HTR7 (0.55) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL1753176 | 0.66 | CSNK1D (0.60) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL1752949 | 0.66 | NPY5R (0.49) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL11815023 | 0.66 | BRD4 (0.36) | HTR2CALDH1A1BRD4 | |
| SCHEMBL20431317 | 0.65 | MEN1 (0.40) | HTR6HTR2CCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3319555 | 0.65 | HTR7 (0.58) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL7261980 | 0.65 | KDM4E (0.76) | HTR7HTR1AHTR6HTR2AHTR5A | |
| SCHEMBL11464180 | 0.64 | KDM4E (0.40) | CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072496-A1 | FORMULATIONS CONTAINING PYRIDAZINE COMPOUNDS | NORTHWESTERN UNIVERSITY (US) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072496-A1 | FORMULATIONS CONTAINING PYRIDAZINE COMPOUNDS | TST, SRMS, STS | HTR7 297/4885HTR1A 1121/4885HTR6 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.