Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.68 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22540393 | 0.89 | OPRM1 (0.58) | OPRM1OPRL1 | |
| SCHEMBL22503703 | 0.86 | OPRM1 (0.65) | OPRM1OPRL1 | |
| SCHEMBL22540404 | 0.85 | OPRM1 (0.70) | OPRM1OPRL1 | |
| SCHEMBL22820284 | 0.83 | OPRM1 (0.66) | OPRM1OPRL1 | |
| SCHEMBL19116741 | 0.82 | OPRM1 (0.57) | OPRM1OPRL1 | |
| SCHEMBL19111115 | 0.81 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19094703 | 0.81 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19094704 | 0.81 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL22503677 | 0.81 | OPRM1 (0.59) | OPRM1OPRL1 | |
| SCHEMBL22503675 | 0.80 | OPRM1 (0.48) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170197919-A1 | 3-(Carboxyethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | GRUENENTHAL GMBH (DE) | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197919-A1 | 3-(Carboxyethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | OPRK1, OPRD1, PKD1 | OPRM1 7/4885OPRL1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.