Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 2/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15791911 | 0.83 | TSHR (0.35) | GRNSORT1TSHR | |
| SCHEMBL14321425 | 0.82 | GRN (0.39) | GRNSORT1TSHR | |
| SCHEMBL19136185 | 0.81 | HSD17B10 (0.36) | TSHRPDE2AADRB2ADRB1 | |
| SCHEMBL19136514 | 0.79 | CYP1A2 (0.35) | TSHRPDE2AADRB2ADRB1 | |
| SCHEMBL31288705 | 0.78 | LMNA (0.41) | TSHRADRB2PDK1PDK2PDK3 | |
| Hydrochloric Acid SCHEMBL31288671 | 0.77 | TSHR (0.40) | TSHRADRB2PDK1PDK2PDK3 | |
| SCHEMBL19136758 | 0.75 | GRN (0.33) | GRNSORT1PDE2A | |
| SCHEMBL19136388 | 0.74 | CES2 (0.42) | PDE2AADRB2ADRB1 | |
| SCHEMBL19136578 | 0.74 | TSHR (0.35) | GRNSORT1TSHR | |
| SCHEMBL15795215 | 0.74 | SLC6A2 (0.40) | AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132014-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2017-08-03 | — | — | WO | disclosed |
| US-20170210723-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2017-07-27 | — | — | US | disclosed |
| US-20170210723-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2017-07-27 | — | — | US | disclosed |
| US-20170210723-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210723-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MSMO1 | GRN 3248/4885SORT1 3348/4885TSHR 3449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.