Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549528 | 0.87 | MEN1 (0.55) | MEN1KMT2AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL561706 | 0.85 | MEN1 (0.64) | MEN1KMT2AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL1059937 | 0.82 | MEN1 (0.67) | MEN1KMT2AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL20795780 | 0.82 | MEN1 (0.50) | MEN1KMT2AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL24082140 | 0.81 | MEN1 (0.59) | MEN1KMT2AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL10622033 | 0.81 | MEN1 (0.59) | MEN1KMT2AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL11507769 | 0.78 | MEN1 (0.61) | MEN1KMT2AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL11839604 | 0.78 | LMNA (0.44) | MEN1KMT2ACA2CA9CA1 | |
| SCHEMBL9621857 | 0.78 | CA1 (0.52) | HPGDCA2CA9CA1LMNA | |
| SCHEMBL1059938 | 0.78 | MEN1 (0.61) | MEN1KMT2AHPGDSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429726-A1 | Process for 2-(aminoalkylthio)carbapenems | MERCK & CO. INC. (US) | 1991-06-05 | — | — | EP | claimed |
| US-4894450-A | FORMING AN ENOL PHOSPHATE INTERMEDIATE | MERCK & CO., INC. (US) | 1990-01-16 | — | — | US | claimed |
| CN-116947924-A | Camptothecin biphosphate compound and preparation method thereof | 上海应用技术大学 | 2023-10-27 | — | — | CN | disclosed |
| US-8883765-B2 | Anti-cytomegalovirus activity of artemisinin-derived dimers | THE JOHN HOPKINS UNIVERSITY (US) | 2014-11-11 | — | — | US | disclosed |
| US-8883765-B2 | Anti-cytomegalovirus activity of artemisinin-derived dimers | THE JOHN HOPKINS UNIVERSITY (US) | 2014-11-11 | — | — | US | disclosed |
| US-8883765-B2 | Anti-cytomegalovirus activity of artemisinin-derived dimers | THE JOHN HOPKINS UNIVERSITY (US) | 2014-11-11 | — | — | US | disclosed |
| US-20130109654-A1 | ANTI-CYTOMEGALOVIRUS ACTIVITY OF ARTEMISININ-DERIVED DIMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109654-A1 | ANTI-CYTOMEGALOVIRUS ACTIVITY OF ARTEMISININ-DERIVED DIMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109654-A1 | ANTI-CYTOMEGALOVIRUS ACTIVITY OF ARTEMISININ-DERIVED DIMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2013-05-02 | — | — | US | disclosed |
| WO-2011071981-A2 | ANTI-CYTOMEGALOVIRUS ACTIVITY OF ARTEMISININ-DERIVED DIMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-06-16 | — | — | WO | disclosed |
| WO-2011071981-A2 | ANTI-CYTOMEGALOVIRUS ACTIVITY OF ARTEMISININ-DERIVED DIMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-06-16 | — | — | WO | disclosed |
| EP-0679652-A1 | Process for preparing carbapenem compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1995-11-02 | — | — | EP | disclosed |
| EP-0331032-B1 | 2'-DEOXY-5-FLUOROURIDINE DERIVATIVES | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5032680-A | Antitumor | KURARAY CO., LTD. (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0429726-A1 | Process for 2-(aminoalkylthio)carbapenems | MERCK & CO. INC. (US) | 1991-06-05 | — | — | EP | disclosed |
| US-4992558-A | Used for dyeing synthetic materials; polyesters | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4894450-A | FORMING AN ENOL PHOSPHATE INTERMEDIATE | MERCK & CO., INC. (US) | 1990-01-16 | — | — | US | disclosed |
| EP-0331032-A1 | 2'-Deoxy-5-fluorouridine derivatives | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1989-09-06 | — | — | EP | disclosed |
| EP-0290583-A1 | -g(a) OLIGONUCLEOTIDES. | CENTRE NAT RECH SCIENT (FR) | 1988-11-17 | — | — | EP | disclosed |
| WO-1988004301-A1 | alpha OLIGONUCLEOTIDES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) | 1988-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109654-A1 | ANTI-CYTOMEGALOVIRUS ACTIVITY OF ARTEMISININ-DERIVED DIMERS | EIF2AK2, MAVS, PARP16 | MEN1 1379/4885KMT2A 4424/4885HPGD 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.