Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1913664 | 0.87 | MEN1 (0.64) | MEN1KMT2AHPGDLMNANPSR1 | |
| SCHEMBL20795780 | 0.82 | MEN1 (0.50) | MEN1KMT2AHPGDLMNANPSR1 | |
| SCHEMBL4433446 | 0.81 | MEN1 (0.57) | MEN1KMT2AHPGDLMNANPSR1 | |
| SCHEMBL11433980 | 0.81 | SRC (0.50) | MEN1KMT2AHPGDLMNAHTT | |
| SCHEMBL561706 | 0.78 | MEN1 (0.64) | MEN1KMT2AHPGDLMNANPSR1 | |
| Potassium Ion SCHEMBL11804339 | 0.76 | MEN1 (0.52) | MEN1KMT2AHPGDLMNANPSR1 | |
| SCHEMBL9549537 | 0.76 | MEN1 (0.52) | MEN1KMT2AHPGDLMNANPSR1 | |
| SCHEMBL8427162 | 0.76 | ALDH1A1 (0.63) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL9621857 | 0.76 | CA1 (0.52) | HPGDLMNAHTTALDH1A1CA1 | |
| SCHEMBL11177722 | 0.76 | MEN1 (0.61) | MEN1KMT2AHPGDLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290583-B1 | $g(a) OLIGONUCLEOTIDES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1993-04-07 | — | — | EP | disclosed |
| EP-0214908-B1 | COMPOUNDS CONTAINING AN OLIGONUCLEOTIDE SEQUENCE LINKED TO AN INTERCALATING AGENT AND TO AN ACTIVABLE CHEMICAL GROUP, THEIR SYNTHESIS AND APPLICATIONS TO ARTIFICIAL SEQUENCE-SPECIFIC NUCLEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1990-11-07 | — | — | EP | disclosed |
| US-4835263-A | Novel compounds containing an oligonucleotide sequence bonded to an intercalating agent, a process for their synthesis and their use | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1989-05-30 | — | — | US | disclosed |
| EP-0117777-B1 | COMPOUNDS CONTAINING AN OLIGONUCLEOTIDE BONDED TO AN INTERCALLATING AGENT, A PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1987-12-23 | — | — | EP | disclosed |
| EP-0214908-A1 | Compounds containing an oligonucleotide sequence linked to an intercalating agent and to an activable chemical group, their synthesis and applications to artificial sequence-specific nucleases | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1987-03-18 | — | — | EP | disclosed |
| EP-0117777-A1 | Compounds containing an oligonucleotide bonded to an intercallating agent, a process for their preparation and their application | Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1984-09-05 | — | — | EP | disclosed |