Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.45 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.45 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305207 | 0.85 | L3MBTL3 (0.49) | ALDH1A1L3MBTL3HSD11B1KMT2APOLB | |
| SCHEMBL19915895 | 0.85 | MGLL (0.56) | MGLLL3MBTL3CA12CA1CA2 | |
| SCHEMBL7809522 | 0.85 | ACHE (0.64) | MGLLL3MBTL3HSD11B1KMT2AMEN1 | |
| SCHEMBL12156431 | 0.80 | ACHE (0.70) | MGLLALDH1A1L3MBTL3CA12CA1 | |
| SCHEMBL28006179 | 0.79 | GFER (0.55) | ALDH1A1ESR1HSD17B10KMT2APOLB | |
| SCHEMBL19127245 | 0.79 | L3MBTL3 (0.43) | ALDH1A1L3MBTL3HSD11B1KMT2APOLB | |
| SCHEMBL31267062 | 0.78 | MGLL (0.61) | MGLLALDH1A1L3MBTL3CA12CA1 | |
| SCHEMBL13575475 | 0.78 | MGLL (0.61) | MGLLALDH1A1L3MBTL3CA12CA1 | |
| SCHEMBL3001302 | 0.78 | MGLL (0.61) | MGLLALDH1A1L3MBTL3CA12CA1 | |
| SCHEMBL19145591 | 0.78 | L3MBTL3 (0.42) | ALDH1A1L3MBTL3HSD11B1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017121444-A1 | QUINOLIN-2-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-07-20 | — | — | WO | disclosed |