Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HINT1 | P49773 | 6/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19145875 | 0.87 | HPGD (0.39) | HPGDHINT1TAS1R3TAS1R1NT5E | |
| SCHEMBL19146252 | 0.86 | KDM4E (0.48) | HPGDHINT1TAS1R3TAS1R1TAAR1 | |
| SCHEMBL19127991 | 0.85 | TYMP (0.52) | HPGDHINT1TAS1R3TAS1R1GSK3A | |
| SCHEMBL19127992 | 0.85 | TYMP (0.52) | HPGDHINT1TAS1R3TAS1R1GSK3A | |
| SCHEMBL19145869 | 0.84 | ADORA3 (0.50) | ADORA2AADORA1 | |
| SCHEMBL26808338 | 0.82 | HINT1 (0.51) | HPGDHINT1TAS1R3TAS1R1GSK3A | |
| SCHEMBL29973359 | 0.82 | HINT1 (0.55) | HPGDHINT1TAS1R3TAS1R1GSK3A | |
| SCHEMBL25390285 | 0.82 | TAS1R3 (0.53) | HPGDHINT1TAS1R3TAS1R1GSK3A | |
| SCHEMBL29479244 | 0.82 | TAS1R3 (0.53) | HPGDHINT1TAS1R3TAS1R1GSK3A | |
| SCHEMBL24377160 | 0.82 | TAS1R3 (0.53) | HPGDHINT1TAS1R3TAS1R1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017123669-A1 | CYCLIC DINUCLEOTIDES FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY SUCH AS CANCER | GLICK GARY (US) | 2017-07-20 | — | — | WO | disclosed |