Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 2/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24811430 | 0.86 | TRPV4 (0.41) | NMT1TRPV4F2TSHRGLA | |
| SCHEMBL27544457 | 0.86 | NMT1 (0.51) | NMT1F2TSHRGLAKMT2A | |
| SCHEMBL11655127 | 0.85 | EPHX2 (0.43) | NMT1TRPV4TSHRGLAKMT2A | |
| SCHEMBL8295856 | 0.84 | NMT1 (0.50) | NMT1F2TSHRGLAKMT2A | |
| SCHEMBL29381119 | 0.82 | NMT1 (0.49) | NMT1F2TSHRGLAKMT2A | |
| SCHEMBL10526657 | 0.82 | NMT1 (0.49) | NMT1F2TSHRGLAKMT2A | |
| SCHEMBL114242 | 0.82 | NMT1 (0.49) | NMT1F2TSHRGLAKMT2A | |
| SCHEMBL3449519 | 0.82 | NMT1 (0.49) | NMT1F2TSHRGLAKMT2A | |
| Hydrochloric Acid SCHEMBL640366 | 0.81 | NMT1 (0.48) | NMT1F2TSHRGLAKMT2A | |
| SCHEMBL14519877 | 0.79 | NMT1 (0.47) | NMT1F2KMT2AAVPR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627832-A | Preparation method for synthesizing tenofovir alafenamide by oxidation method | 江西农业大学 | 2019-12-31 | — | — | CN | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| WO-2005037811-A1 | A METHOD FOR THE PRODUCTION OF CHIRAL SUBSTITUTED EPOXIDES | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO. KG (AT) | 2005-04-28 | — | — | WO | claimed |
| US-4487726-A | USED IN SYNTHESIS OF PEPTIDES CONTAINING GAUNIDING GROUP | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-12-11 | — | — | US | claimed |
| JP-2049799-A | — | — | None | — | — | JP | disclosed |
| JP-1151549-A | — | — | None | — | — | JP | disclosed |
| JP-2015094-A | — | — | None | — | — | JP | disclosed |
| JP-1151550-A | — | — | None | — | — | JP | disclosed |
| US-11773057-B2 | Naphthalenesulfonamide compound, preparation method, and application | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2023-10-03 | — | — | US | disclosed |
| EP-3978471-B1 | NAPHTHALENESULFONAMIDE COMPOUND, PREPARATION METHOD, AND APPLICATION | UNIV CHINA PHARMA (CN) | 2023-02-22 | — | — | EP | disclosed |
| US-20220251035-A1 | NAPHTHALENESULFONAMIDE COMPOUND, PREPARATION METHOD, AND APPLICATION | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2022-08-11 | — | — | US | disclosed |
| EP-3978471-A1 | NAPHTHALENESULFONAMIDE COMPOUND, PREPARATION METHOD, AND APPLICATION | China Pharmaceutical University (CN) | 2022-04-06 | — | — | EP | disclosed |
| EP-0056274-B1 | INDOLE DERIVATIVES AND A METHOD FOR PRODUCTION OF PEPTIDES | Takeda Chemical Industries, Ltd. (JP) | 1984-05-09 | — | — | EP | disclosed |
| US-4416820-A | Indole derivatives and a method for production of peptides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-11-22 | — | — | US | disclosed |
| EP-0078498-A1 | Method for protecting amino group and restoring the same | Takeda Chemical Industries, Ltd. (JP) | 1983-05-11 | — | — | EP | disclosed |
| US-4368150-A | WITH A BENZENESULFONYL COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-01-11 | — | — | US | disclosed |
| EP-0056274-A1 | Indole derivatives and a method for production of peptides | Takeda Chemical Industries, Ltd. (JP) | 1982-07-21 | — | — | EP | disclosed |
| EP-0033976-A2 | Method for protecting guanidino group and restoring the same | Takeda Chemical Industries, Ltd. (JP) | 1981-08-19 | — | — | EP | disclosed |
| JP-H00249799-A | — | — | 0001-01-01 | — | — | JP | disclosed |
| JP-H00215094-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773057-B2 | Naphthalenesulfonamide compound, preparation method, and application | NFE2L2, KEAP1, NFE2 | NMT1 394/4885TRPV4 1526/4885F2 2539/4885 |
| US-20220251035-A1 | NAPHTHALENESULFONAMIDE COMPOUND, PREPARATION METHOD, AND APPLICATION | NFE2L2, KEAP1, NFE2 | NMT1 394/4885TRPV4 1526/4885F2 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.