Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20657440 | 1.00 | MPI (0.42) | MPIHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20657441 | 0.83 | HTR3E (0.60) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL19148202 | 0.83 | HTR3E (0.60) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20657404 | 0.81 | MPI (0.44) | MPIHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20657403 | 0.81 | MPI (0.44) | MPIHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL19150085 | 0.81 | NOS3 (0.51) | POLBNOS1EPHX2 | |
| SCHEMBL20657417 | 0.81 | NOS3 (0.51) | POLBNOS1EPHX2 | |
| SCHEMBL20657453 | 0.76 | HTR3E (0.60) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20657448 | 0.76 | HTR3E (0.60) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20657429 | 0.74 | NOS1 (0.44) | LMNAPOLBNOS1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266494-B2 | Process for the preparation of polyfluoroalkylated quinolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-23 | — | — | US | disclosed |
| US-20190023659-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-24 | — | — | US | disclosed |
| EP-3405458-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | Bayer CropScience Aktiengesellschaft (DE) | 2018-11-28 | — | — | EP | disclosed |
| WO-2017125318-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023659-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | KCNQ1, KCNQ2, KCNQ4 | MPI 1968/4885HTR3E 1006/4885HTR3B 571/4885 |
| US-10266494-B2 | Process for the preparation of polyfluoroalkylated quinolines | KCNQ1, KCNQ2, KCNQ4 | MPI 1968/4885HTR3E 1006/4885HTR3B 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.