Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPRS1 | P07814 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19148974 | 0.83 | PPARA (0.38) | TDP1L3MBTL1ALDH1A1LMNAKMT2A | |
| SCHEMBL19148214 | 0.80 | KCNH2 (0.36) | EPRS1TDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL19148561 | 0.77 | ADORA2A (0.39) | TDP1L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL22084257 | 0.70 | LMNA (0.38) | TDP1L3MBTL1LMNA | |
| SCHEMBL19150087 | 0.69 | KDM4E (0.43) | KDM4EALDH1A1LMNA | |
| SCHEMBL19150086 | 0.68 | POLB (0.43) | ALDH1A1KMT2A | |
| SCHEMBL19148959 | 0.68 | ACHE (0.36) | TDP1L3MBTL1KDM4EKMT2A | |
| SCHEMBL13905092 | 0.66 | LMNA (0.50) | EPRS1TDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL19554032 | 0.66 | MAPT (0.42) | EPRS1TDP1L3MBTL1KDM4ELMNA | |
| SCHEMBL19150075 | 0.66 | ENPP1 (0.44) | TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266494-B2 | Process for the preparation of polyfluoroalkylated quinolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-23 | — | — | US | disclosed |
| US-20190023659-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-24 | — | — | US | disclosed |
| EP-3405458-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | Bayer CropScience Aktiengesellschaft (DE) | 2018-11-28 | — | — | EP | disclosed |
| WO-2017125318-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023659-A1 | PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLATED QUINOLINES | KCNQ1, KCNQ2, KCNQ4 | EPRS1 2324/4885TDP1 2627/4885L3MBTL1 4162/4885 |
| US-10266494-B2 | Process for the preparation of polyfluoroalkylated quinolines | KCNQ1, KCNQ2, KCNQ4 | EPRS1 2324/4885TDP1 2627/4885L3MBTL1 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.