Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19148561 | 0.89 | ADORA2A (0.39) | LMNAADORA2AADORA1TDP1L3MBTL1 | |
| SCHEMBL20277896 | 0.81 | LMNA (0.43) | LMNAADORA2ATRPV4ADORA1TDP1 | |
| SCHEMBL22041584 | 0.78 | ADORA2A (0.41) | ADORA2AADORA1L3MBTL1GRM2CYP2D6 | |
| SCHEMBL29659722 | 0.78 | ADORA2A (0.41) | ADORA2AADORA1L3MBTL1GRM2CYP2D6 | |
| SCHEMBL13409387 | 0.75 | LMNA (0.35) | LMNAADORA2AHTR2BADORA1CYP2D6 | |
| SCHEMBL19150087 | 0.71 | KDM4E (0.43) | LMNAPARP1TNKSTNKS2 | |
| SCHEMBL21173367 | 0.70 | PARP1 (0.41) | LMNAADORA2AADORA1L3MBTL1AURKA | |
| SCHEMBL19149180 | 0.70 | EPRS1 (0.36) | LMNATDP1L3MBTL1 | |
| SCHEMBL19148554 | 0.69 | KCNH2 (0.42) | LMNAADORA2AHTR2BADORA1GRM2 | |
| SCHEMBL29659679 | 0.68 | ADORA2A (0.35) | ADORA2AADORA1TDP1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113554-A1 | QUINOLINE DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-11 | — | — | WO | disclosed |