SCHEMBL19150258

SCHEMBL19150258

CCS(=O)(=O)c1c(-c2nc3cc(C(F)(F)F)ncc3n2C)nc2sc(C(F)(F)F)cn12

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KCNH2 Q12809 1/20 0.30
RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19174416 0.85 MET (0.33) KCNH2
SCHEMBL19148978 0.83
SCHEMBL20393874 0.83 LMNA (0.35) NPC1RAB9AKCNH2RORC
SCHEMBL19149238 0.82 ALPI (0.31)
SCHEMBL19148231 0.82
SCHEMBL20379034 0.82 KCNH2 (0.33) NPC1RAB9AKCNH2RORC
SCHEMBL30194810 0.82 KCNH2 (0.33) NPC1RAB9AKCNH2RORC
SCHEMBL31207155 0.81 TRPA1 (0.36) KCNH2RORC
SCHEMBL21805957 0.81 TRPA1 (0.36) KCNH2RORC
SCHEMBL19712002 0.81 POLB (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017125340-A1 CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-07-27 WO disclosed
WO-2017125340-A1 CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-07-27 WO disclosed