Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26438880 | 0.82 | CYP1A2 (0.37) | TSHRCYP1A2CYP3A4HPGDPRNP | |
| SCHEMBL23978475 | 0.81 | MAPT (0.44) | TSHRCYP1A2CYP3A4PRNPRXFP1 | |
| SCHEMBL24174451 | 0.78 | TLR7 (0.34) | LMNATSHRGABRA1GABRG2GABRB3 | |
| SCHEMBL24702582 | 0.78 | MAPT (0.53) | LMNACYP1A2PIP4K2CMAPTKMT2A | |
| SCHEMBL22672620 | 0.77 | HTT (0.41) | TSHRCA1CA2HPGDPOLB | |
| SCHEMBL22672522 | 0.77 | PDE7A (0.44) | TSHRPRNPRXFP1USP2NPSR1 | |
| SCHEMBL24768800 | 0.75 | LMNA (0.57) | LMNATSHRCYP3A4HIF1APRNP | |
| SCHEMBL31326061 | 0.73 | CYP1A2 (0.43) | LMNACYP1A2HPGDPRNPRXFP1 | |
| SCHEMBL4547884 | 0.73 | CYP1A2 (0.43) | LMNACYP1A2HPGDPRNPRXFP1 | |
| SCHEMBL24175176 | 0.73 | GABRA1 (0.38) | LMNATSHRGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022002118-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL USE THEREOF | 四川海思科制药有限公司 | 2022-01-06 | — | — | WO | disclosed |
| US-9744169-B2 | Compounds for treatment of fibrosis diseases | CUREGENIX, INC. (CN) | 2017-08-29 | — | — | US | disclosed |
| US-9713612-B2 | Compounds for treatment of cancer | CUREGENIX, INC. (CN) | 2017-07-25 | — | — | US | disclosed |