Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19154658 | 0.78 | LMNA (0.36) | TLR7ELANELMNACYP1A2CYP3A4 | |
| SCHEMBL4548620 | 0.78 | CA2 (0.36) | ELANELMNATSHRALDH1A1CA2 | |
| SCHEMBL10220808 | 0.77 | CCNE2 (0.36) | TLR7ELANELMNAALDH1A1PLA2G1B | |
| SCHEMBL10220806 | 0.77 | MAPT (0.44) | LMNACYP1A2CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL24702582 | 0.74 | MAPT (0.53) | LMNACYP1A2MAPTPIP4K2C | |
| SCHEMBL20047599 | 0.73 | CCR4 (0.39) | TLR7ELANELMNACYP1A2CYP3A4 | |
| SCHEMBL25054655 | 0.71 | TNF (0.43) | LMNAALDH1A1KDM4EMAPK1MAPT | |
| SCHEMBL24768886 | 0.70 | LMNA (0.56) | ELANELMNACYP3A4TSHRALDH1A1 | |
| SCHEMBL21398081 | 0.70 | — | — | |
| SCHEMBL322264 | 0.70 | CYP1A2 (0.42) | LMNACYP1A2HPGDALDH1A1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022002118-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL USE THEREOF | 四川海思科制药有限公司 | 2022-01-06 | — | — | WO | disclosed |