Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18976231 | 0.76 | JAK2 (0.37) | JAK2BTK | |
| SCHEMBL16183639 | 0.67 | JAK2 (0.51) | JAK2BTK | |
| SCHEMBL20562727 | 0.67 | KDM4E (0.38) | — | |
| SCHEMBL19155521 | 0.66 | TSHR (0.39) | JAK2BTK | |
| SCHEMBL1722016 | 0.65 | TSHR (0.41) | JAK2BTK | |
| SCHEMBL20145970 | 0.65 | JAK2 (0.39) | JAK2BTK | |
| SCHEMBL17699662 | 0.65 | BTK (0.40) | JAK2BTK | |
| SCHEMBL29782721 | 0.65 | BTK (0.40) | JAK2BTK | |
| SCHEMBL562324 | 0.65 | LMNA (0.40) | JAK2BTK | |
| SCHEMBL16034519 | 0.64 | JAK2 (0.40) | JAK2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714234-B2 | Carbazole carboxamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-25 | — | — | US | disclosed |