Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 16/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 16/20 | 0.41 |
| ▸ | ITGAL | P20701 | 16/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13435928 | 0.77 | ITGB2 (0.58) | ITGB2ICAM1ITGAL | |
| SCHEMBL23176447 | 0.75 | ITGB2 (0.62) | ITGB2ICAM1ITGAL | |
| SCHEMBL18867800 | 0.75 | ITGB2 (0.62) | ITGB2ICAM1ITGAL | |
| SCHEMBL19157560 | 0.72 | ITGB2 (0.70) | ITGB2ICAM1ITGAL | |
| SCHEMBL4755996 | 0.72 | ITGB2 (0.80) | ITGB2ICAM1ITGAL | |
| SCHEMBL13894233 | 0.71 | ITGB2 (0.49) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL18867998 | 0.69 | HDAC6 (0.39) | HDAC6ITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL18868119 | 0.68 | HDAC6 (0.50) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL23979102 | 0.68 | ITGB2 (0.58) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL10129657 | 0.66 | ITGB2 (0.62) | HDAC6ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3195861-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DRY EYE DISORDERS | SARcode Bioscience Inc. (US) | 2017-07-26 | — | — | EP | disclosed |