Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 2/20 | 0.40 |
| ▸ | F3 | P13726 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17503821 | 0.85 | F7 (0.40) | F7F3SLC6A2SLC6A4HTR1A | |
| SCHEMBL19158869 | 0.79 | HTT (0.40) | KDM4CLATS1 | |
| SCHEMBL19158876 | 0.75 | KDM4C (0.41) | KDM4CLATS1 | |
| SCHEMBL17503670 | 0.74 | MAPK1 (0.42) | F7F3DHODHF10MAPK1 | |
| SCHEMBL19159348 | 0.73 | ALDH1A1 (0.41) | KDM4CLATS1ALDH1A1 | |
| SCHEMBL19158957 | 0.72 | CXCR2 (0.44) | F7F3DHODHF10CXCR2 | |
| SCHEMBL19158797 | 0.72 | PTGS1 (0.46) | MAPK1KDM4CALDH1A1 | |
| SCHEMBL19159015 | 0.72 | CXCR2 (0.44) | F7F3DHODHF10CXCR2 | |
| SCHEMBL19158281 | 0.69 | KDM4C (0.51) | KDM4CPIP4K2ALATS1 | |
| SCHEMBL19158774 | 0.69 | KDM4C (0.39) | KDM4CLATS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970211-B1 | HISTONE DEMETHYLASE INHIBITORS | QUANTICEL PHARMACEUTICALS INC (US) | 2017-07-26 | — | — | EP | disclosed |