Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 2/20 | 0.40 |
| ▸ | F3 | P13726 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | LATS1 | O95835 | 12/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LATS2 | Q9NRM7 | 8/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19176153 | 0.90 | DHODH (0.41) | CXCR2F7F3DHODHLATS1 | |
| SCHEMBL19158259 | 0.76 | LATS1 (0.41) | LATS1LATS2 | |
| SCHEMBL19158871 | 0.75 | DHFR (0.37) | CXCR2F7F3LATS1LATS2 | |
| SCHEMBL19159014 | 0.72 | F7 (0.40) | CXCR2F7F3DHODHLATS1 | |
| SCHEMBL19158957 | 0.72 | CXCR2 (0.44) | CXCR2F7F3DHODHLATS1 | |
| SCHEMBL19158131 | 0.66 | F7 (0.40) | CXCR2F7F3DHODHLATS1 | |
| SCHEMBL13335778 | 0.65 | LATS1 (0.42) | DHODHLATS1LATS2 | |
| SCHEMBL576234 | 0.64 | NOTUM (0.42) | CXCR2 | |
| SCHEMBL30452252 | 0.64 | NOTUM (0.42) | CXCR2 | |
| SCHEMBL19158253 | 0.64 | KDM4E (0.37) | CXCR2LATS1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970211-B1 | HISTONE DEMETHYLASE INHIBITORS | QUANTICEL PHARMACEUTICALS INC (US) | 2017-07-26 | — | — | EP | disclosed |