Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LATS1 | O95835 | 5/20 | 0.39 |
| ▸ | LATS2 | Q9NRM7 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.36 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19158774 | 0.81 | KDM4C (0.39) | LATS1LATS2KDM4CACHE | |
| SCHEMBL19158281 | 0.81 | KDM4C (0.51) | LATS1LATS2KDM4CACHE | |
| SCHEMBL16095498 | 0.81 | HASPIN (0.39) | HASPINIDO1LATS1LATS2KDM4C | |
| SCHEMBL13335778 | 0.77 | LATS1 (0.42) | LATS1LATS2KDM4CACHE | |
| SCHEMBL19158869 | 0.77 | HTT (0.40) | IDO1LATS1LATS2KDM4C | |
| SCHEMBL26313710 | 0.76 | GPR3 (0.55) | ALDH1A1ACHEMAOAPOLBSMN1; SMN2 | |
| SCHEMBL19158161 | 0.75 | HRH3 (0.45) | LATS1LATS2KDM4CMAOA | |
| SCHEMBL15515002 | 0.74 | CYP1A2 (0.58) | ALDH1A1LATS1LATS2KDM4CACHE | |
| SCHEMBL19158876 | 0.74 | KDM4C (0.41) | IDO1LATS1LATS2KDM4C | |
| SCHEMBL19159014 | 0.73 | F7 (0.40) | ALDH1A1LATS1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970211-B1 | HISTONE DEMETHYLASE INHIBITORS | QUANTICEL PHARMACEUTICALS INC (US) | 2017-07-26 | — | — | EP | disclosed |