Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | LATS1 | O95835 | 7/20 | 0.40 |
| ▸ | LATS2 | Q9NRM7 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 2/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26157957 | 0.80 | DCPS (0.55) | CYP1A2ACHELMNACYP3A4CYP2D6 | |
| SCHEMBL13335778 | 0.80 | LATS1 (0.42) | ACHELATS1LATS2DHODHKDM4C | |
| Ammonia Solution, Strong SCHEMBL29288477 | 0.78 | ACHE (0.44) | CYP1A2ACHELATS1LATS2LMNA | |
| SCHEMBL27109643 | 0.78 | LATS1 (0.43) | ACHELATS1LATS2DHODHKDM4C | |
| SCHEMBL13169638 | 0.77 | GPR3 (0.64) | CYP1A2ALDH1A1HPGDNUDT1HSD17B10 | |
| SCHEMBL19159348 | 0.74 | ALDH1A1 (0.41) | ALDH1A1ACHELATS1LATS2KDM4C | |
| SCHEMBL31375930 | 0.74 | ADORA2A (0.53) | NUDT1ACHELATS1LATS2 | |
| SCHEMBL19158887 | 0.74 | KDM4C (0.42) | ACHELATS1LATS2KDM4C | |
| SCHEMBL377227 | 0.74 | HSD17B10 (1.00) | CYP1A2ALDH1A1HPGDNUDT1HSD17B10 | |
| SCHEMBL30080783 | 0.74 | HSD17B10 (1.00) | CYP1A2ALDH1A1HPGDNUDT1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892889-A1 | INHIBITOR COMPOUNDS | Cancer Research Technology Ltd (GB) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014037750-A1 | INHIBITOR COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2014-03-13 | — | — | WO | disclosed |