Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | PCK1 | P35558 | 1/20 | 0.39 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.39 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1913043 | 0.95 | C5AR1 (0.42) | C5AR1PCK1TSSK1BMOKMAPT | |
| SCHEMBL1913044 | 0.92 | RORC (0.46) | C5AR1PCK1TSSK1BMOKMAPT | |
| SCHEMBL5135444 | 0.89 | C5AR1 (0.47) | BCHEC5AR1HPGD | |
| SCHEMBL1915973 | 0.88 | C5AR1 (0.42) | C5AR1HPGD | |
| SCHEMBL649926 | 0.88 | MAPT (0.42) | C5AR1PCK1TSSK1BMAPT | |
| SCHEMBL649563 | 0.86 | C5AR1 (0.61) | C5AR1HPGDNPC1 | |
| SCHEMBL5136942 | 0.85 | C5AR1 (0.46) | C5AR1HPGD | |
| SCHEMBL649496 | 0.83 | C5AR1 (0.44) | C5AR1HPGD | |
| SCHEMBL5136767 | 0.83 | C5AR1 (0.41) | C5AR1 | |
| SCHEMBL1915525 | 0.83 | C5AR1 (0.44) | C5AR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119665-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2012-02-21 | — | — | US | disclosed |