Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.53 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3028458 | 0.96 | HSD17B10 (0.49) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL29263924 | 0.85 | HSD17B10 (0.67) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL3011991 | 0.80 | HSD17B10 (0.54) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL8521624 | 0.80 | HSD17B10 (0.58) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL754554 | 0.80 | HSD17B10 (0.58) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL1476385 | 0.79 | HSD17B10 (0.56) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL29249658 | 0.78 | HSD17B10 (0.56) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL29249729 | 0.78 | HSD17B10 (0.56) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL12245566 | 0.78 | CA12 (0.61) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL15182687 | 0.77 | HSD17B10 (0.54) | HSD17B10KMT2ATARDBPTSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053706-A1 | COMPOSITION COMPRISING PAEONIFLORIN OR ALBIFLORIN ANALOGUE, METHOD OF PREPARATION THEREOF | L'OREAL (FR) | 2018-03-29 | — | — | WO | disclosed |
| EP-2640423-B1 | LIPOYL COMPOUNDS AND THEIR USE FOR TREATING ISCHEMIC INJURY | ISCHEMIX LLC (US) | 2017-07-26 | — | — | EP | disclosed |