Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19160682 | 0.96 | HSD17B10 (0.53) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL29263924 | 0.80 | HSD17B10 (0.67) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL22472997 | 0.77 | HSD17B10 (0.54) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL3011991 | 0.77 | HSD17B10 (0.54) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL284930 | 0.77 | — | — | |
| SCHEMBL8521624 | 0.76 | HSD17B10 (0.58) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL754554 | 0.76 | HSD17B10 (0.58) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL1476385 | 0.75 | HSD17B10 (0.56) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL29249658 | 0.74 | HSD17B10 (0.56) | HSD17B10KMT2ATARDBPTSHRCYP2C9 | |
| SCHEMBL29249729 | 0.74 | HSD17B10 (0.56) | HSD17B10KMT2ATARDBPTSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198390-B2 | Self assembled grafted polymeric layer for use in biosensor technology | IMEC (BE) | 2012-06-12 | — | — | US | disclosed |
| US-20100204415-A1 | SELFASSEMBLED GRAFTED POLYMERIC LAYER FOR USE IN BIOSENSOR TECHNOLOGY | IMEC (BE) | 2010-08-12 | — | — | US | disclosed |
| US-7728094-B2 | Selfassembled grafted polymeric layer for use in biosensor technology | IMEC (BE) | 2010-06-01 | — | — | US | disclosed |
| US-20060252094-A1 | Selfassembled grafted polymeric layer for use in biosensor technology | IMEC (BE) | 2006-11-09 | — | — | US | disclosed |