Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.71 |
| ▸ | MMP2 | P08253 | 2/20 | 0.71 |
| ▸ | MMP8 | P22894 | 2/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.71 |
| ▸ | TYR | P14679 | 3/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.63 |
| ▸ | MMP13 | P45452 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | PTGES | O14684 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12299018 | 0.92 | TYR (0.73) | MMP9NFKB1TYRACHETRPV1 | |
| SCHEMBL1916293 | 0.92 | TYR (0.73) | MMP9NFKB1TYRACHETRPV1 | |
| SCHEMBL9921168 | 0.90 | TYR (0.80) | MMP9MMP2MMP8NFKB1TYR | |
| SCHEMBL9921165 | 0.90 | TYR (0.80) | MMP9MMP2MMP8NFKB1TYR | |
| SCHEMBL7521409 | 0.90 | TYR (0.79) | MMP9NFKB1TYRACHETRPV1 | |
| SCHEMBL7521416 | 0.90 | TYR (0.79) | MMP9NFKB1TYRACHETRPV1 | |
| SCHEMBL7523925 | 0.87 | TYR (0.71) | MMP9MMP2NFKB1TYRACHE | |
| SCHEMBL14164369 | 0.87 | TYR (0.70) | MMP9NFKB1TYRACHETRPV1 | |
| SCHEMBL7523933 | 0.87 | TYR (0.71) | MMP9MMP2NFKB1TYRACHE | |
| SCHEMBL12246735 | 0.85 | TYR (0.63) | MMP9NFKB1TYRACHETRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160067171-A1 | ORAL AND DENTAL HYGIENE AND CLEANING AGENTS WITH OPTIMIZED TASTE | HENKEL AG & CO. KGAA (DE) | 2016-03-10 | — | — | US | disclosed |
| US-20160067168-A1 | ORAL AND DENTAL HYGIENE AND CLEANING AGENTS FOR SENSITIVE TEETH | HENKEL AG & CO. KGAA (DE) | 2016-03-10 | — | — | US | disclosed |
| US-20160067169-A1 | TOOTHPASTE CONTAINING FLUORIDE AND POLYLACTIC ACID PARTICLES | HENKEL AG & CO. KGAA (DE) | 2016-03-10 | — | — | US | disclosed |
| US-20160067170-A1 | ORAL AND DENTAL HYGIENE AND CLEANING AGENTS WITH IMPROVED ANTI-BACTERIAL ACTION | HENKEL AG & CO. KGAA (DE) | 2016-03-10 | — | — | US | disclosed |
| EP-2476406-A2 | Oral and tooth care and cleaning agents with improved antibacterial effect II | Henkel AG & Co. KGaA (DE) | 2012-07-18 | — | — | EP | disclosed |
| EP-2462916-A2 | Oral and tooth care and cleaning agents with improved antibacterial effect I | Henkel AG & Co. KGaA (DE) | 2012-06-13 | — | — | EP | disclosed |
| EP-2347754-A2 | Oral and tooth care and cleaning agents with alkylpyridine salts I | Henkel AG & Co. KGaA (DE) | 2011-07-27 | — | — | EP | disclosed |
| EP-2332514-A1 | Antibacterial oral and tooth care and cleaning agents with silver | Henkel AG & Co. KGaA (DE) | 2011-06-15 | — | — | EP | disclosed |
| EP-2111853-A1 | Oral and tooth care and cleaning agents with pomegranate extract | Henkel AG & Co. KGaA (DE) | 2009-10-28 | — | — | EP | disclosed |
| EP-2025319-A2 | Numbing oral and tooth care and cleaning agents | Henkel AG & Co. KGaA (DE) | 2009-02-18 | — | — | EP | disclosed |
| EP-1880705-A2 | Brightening and/or colouring composition with improved product sensation | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-23 | — | — | EP | disclosed |
| EP-1842573-A2 | Brightening and/or colouring agent with improved product sensation | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2007085428-A2 | MOUTH AND TOOTH CARE AND CLEANSING AGENT COMPRISING ENZYMES | HENKEL AG & CO. KGAA (DE) | 2007-08-02 | — | — | WO | disclosed |
| EP-1806126-A1 | Dental preparations comprising enzymes | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-07-11 | — | — | EP | disclosed |
| EP-1806124-A1 | Dental preparations comprising enzymes | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-07-11 | — | — | EP | disclosed |
| WO-2007068403-A2 | REMINERALIZING PRODUCTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-06-21 | — | — | WO | disclosed |
| EP-1774954-A2 | Mouthwash and dentifrice and cleansing composition | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-04-18 | — | — | EP | disclosed |
| EP-1774953-A2 | Mouthwash concentrate | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-04-18 | — | — | EP | disclosed |
| EP-1774956-A2 | Mouthwash and dentifrice and cleansing composition | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-04-18 | — | — | EP | disclosed |
| EP-1774955-A2 | Ready-to-use mounthwash | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160067170-A1 | ORAL AND DENTAL HYGIENE AND CLEANING AGENTS WITH IMPROVED ANTI-BACTERIAL ACTION | USP39, USP30, SOD1 | MMP9 625/4885MMP2 1098/4885MMP8 1351/4885 |
| US-20160067168-A1 | ORAL AND DENTAL HYGIENE AND CLEANING AGENTS FOR SENSITIVE TEETH | SI, H1-0, POLD1 | MMP9 2356/4885MMP2 1331/4885MMP8 1784/4885 |
| US-20160067171-A1 | ORAL AND DENTAL HYGIENE AND CLEANING AGENTS WITH OPTIMIZED TASTE | SORD, TAS2R40, TREH | MMP9 3679/4885MMP2 3696/4885MMP8 3272/4885 |
| US-20160067169-A1 | TOOTHPASTE CONTAINING FLUORIDE AND POLYLACTIC ACID PARTICLES | PUF60, POLI, FIP1L1 | MMP9 1080/4885MMP2 808/4885MMP8 873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.