Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.71 |
| ▸ | ACHE | P22303 | 1/20 | 0.71 |
| ▸ | MMP9 | P14780 | 2/20 | 0.65 |
| ▸ | MMP1 | P03956 | 1/20 | 0.65 |
| ▸ | MMP2 | P08253 | 1/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | PTGES | O14684 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.60 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523933 | 1.00 | TYR (0.71) | TYRACHEMMP9MMP1MMP2 | |
| SCHEMBL7521409 | 0.95 | TYR (0.79) | TYRACHEMMP9TRPV1CYP2D6 | |
| SCHEMBL7521416 | 0.95 | TYR (0.79) | TYRACHEMMP9TRPV1CYP2D6 | |
| SCHEMBL1916293 | 0.95 | TYR (0.73) | TYRACHEMMP9TRPV1CYP2D6 | |
| SCHEMBL12299018 | 0.95 | TYR (0.73) | TYRACHEMMP9TRPV1CYP2D6 | |
| SCHEMBL12246735 | 0.91 | TYR (0.63) | TYRACHEMMP9TRPV1CYP2D6 | |
| SCHEMBL7531081 | 0.90 | MMP1 (0.65) | TYRACHEMMP9MMP1MMP2 | |
| SCHEMBL7531089 | 0.90 | MMP1 (0.65) | TYRACHEMMP9MMP1MMP2 | |
| SCHEMBL802713 | 0.90 | ABCB1 (0.65) | TYRACHEMMP9TRPV1HDAC3 | |
| SCHEMBL2847215 | 0.89 | TYR (0.61) | TYRACHEMMP9TRPV1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900781-B1 | Phenolic acid amides of hydroxy substituted benzylamines | HAARMANN & REIMER GMBH (DE) | 2002-03-20 | — | — | EP | claimed |
| US-6117365-A | N-(3,4-DIHYDROXYBENZYL)-3,5-DIMETHOXY-4-HYDROXY-E-CINNAMIDE, FOR EXAMPLE; USE AS ANTIOXIDANTS OR AS FREE-RADICAL SCAVENGERS, IN PARTICULAR IN THE COSMETIC OR DERMATOLOGICAL FIELDS, AND IN FOODS | HAARMANN & REIMER GMBH (DE) | 2000-09-12 | — | — | US | claimed |
| US-9089499-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | UNIVERSITE JOSEPH FOURIER-GRENOBLE 1 (FR) | 2015-07-28 | — | — | US | disclosed |
| US-9089499-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | UNIVERSITE JOSEPH FOURIER-GRENOBLE 1 (FR) | 2015-07-28 | — | — | US | disclosed |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | Universite Joseph Fourier-Grenoble 1. (FR) | 2013-10-17 | — | — | US | disclosed |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | Universite Joseph Fourier-Grenoble 1. (FR) | 2013-10-17 | — | — | US | disclosed |
| US-8481593-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS S.A.S. (FR) | 2013-07-09 | — | — | US | disclosed |
| US-8481593-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS S.A.S. (FR) | 2013-07-09 | — | — | US | disclosed |
| US-20110237551-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2011-09-29 | — | — | US | disclosed |
| US-20110237551-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2011-09-29 | — | — | US | disclosed |
| US-20070183996-A1 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2007-08-09 | — | — | US | disclosed |
| US-20070183996-A1 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2007-08-09 | — | — | US | disclosed |
| US-6117365-A | N-(3,4-DIHYDROXYBENZYL)-3,5-DIMETHOXY-4-HYDROXY-E-CINNAMIDE, FOR EXAMPLE; USE AS ANTIOXIDANTS OR AS FREE-RADICAL SCAVENGERS, IN PARTICULAR IN THE COSMETIC OR DERMATOLOGICAL FIELDS, AND IN FOODS | HAARMANN & REIMER GMBH (DE) | 2000-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237551-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions | TYR, CUTA, HPD | TYR 1/4885ACHE 1052/4885MMP9 553/4885 |
| US-20070183996-A1 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | TYR, CUTA, HPD | TYR 1/4885ACHE 1070/4885MMP9 605/4885 |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | TYR, CUTA, HPD | TYR 1/4885ACHE 1070/4885MMP9 605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.