Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1916634 | 0.80 | MAPT (0.49) | MAPTNOTUMARALDH1A1MEN1 | |
| SCHEMBL28782710 | 0.74 | NOTUM (0.40) | NOTUMMGLLALDH1A1MEN1KMT2A | |
| SCHEMBL19725777 | 0.74 | ALDH1A1 (0.42) | MAPTMGLLALDH1A1MEN1KMT2A | |
| SCHEMBL17576293 | 0.70 | ALDH1A1 (0.36) | MAPTARMGLLALDH1A1MEN1 | |
| SCHEMBL19230062 | 0.70 | ALDH1A1 (0.36) | MAPTARMGLLALDH1A1MEN1 | |
| SCHEMBL15396987 | 0.70 | ALDH1A1 (0.36) | MAPTARMGLLALDH1A1MEN1 | |
| SCHEMBL21025575 | 0.70 | ALDH1A1 (0.36) | MAPTNOTUMARMGLLALDH1A1 | |
| SCHEMBL1918395 | 0.69 | ALDH1A1 (0.40) | NOTUMMGLLALDH1A1HTT | |
| SCHEMBL3436354 | 0.69 | MAPT (0.60) | MAPTNOTUMARALDH1A1TSHR | |
| SCHEMBL1917441 | 0.68 | KDM4E (0.36) | MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218793-A | Method for preparing polyester polyol by catalysis of carbene derivative | NANJING UNIVERSITY OF TECHNOLOGY | 2016-01-06 | — | — | CN | claimed |
| EP-2392606-B1 | PREPARATION METHOD OF POLYLACTIC ACID BY CATALYSIS OF CARBENE DERIVATIVES | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2018-03-28 | — | — | EP | disclosed |
| CN-105218793-A | Method for preparing polyester polyol by catalysis of carbene derivative | NANJING UNIVERSITY OF TECHNOLOGY | 2016-01-06 | — | — | CN | disclosed |
| US-9040653-B2 | Ring-opening polymerization of cyclic compounds catalyzed by carbene derivatives | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2015-05-26 | — | — | US | disclosed |
| US-9029497-B2 | Method of making polylactic acid using carbene derivatives as the catalyst | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2015-05-12 | — | — | US | disclosed |
| EP-2327736-B1 | METHOD OF ADJUSTABLE AND CONTROLLABLE RING-OPENING POLYMERIZATION OF CYCLIC COMPOUNDS BY CATALYSIS OF CARBENE DERIVATIVES | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2015-03-18 | — | — | EP | disclosed |
| US-20110152493-A1 | METHOD OF MAKING POLYLACTIC ACID USING CARBENE DERIVATIVES AS THE CATALYST | NANJING UNIVERSITY OF TECHNOLOGY | 2011-06-23 | — | — | US | disclosed |
| US-20110144296-A1 | RING-OPENING POLYMERIZATION OF CYCLIC COMPOUNDS CATALYZED BY CARBENE DERIVATIVES | NANJING UNIVERSITY OF TECHNOLOGY | 2011-06-16 | — | — | US | disclosed |
| EP-2327736-A1 | METHOD OF ADJUSTABLE AND CONTROLLABLE RING-OPENING POLYMERIZATION OF CYCLIC COMPOUNDS BY CATALYSIS OF CARBENE DERIVATIVES | Nanjing University of Technology (CN) | 2011-06-01 | — | — | EP | disclosed |