Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.31 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAPDH | P04406 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16678755 | 0.81 | FABP4 (0.34) | ALDH1A1HPGDRECQLMAPTFABP4 | |
| SCHEMBL1917895 | 0.79 | MAPT (0.40) | KDM4ETPMTALDH1A1HPGDRECQL | |
| SCHEMBL16678647 | 0.78 | MAPT (0.33) | ALDH1A1HPGDRECQLMAPTFABP4 | |
| SCHEMBL16678644 | 0.73 | MAPT (0.35) | KDM4ETPMTALDH1A1HPGDLMNA | |
| SCHEMBL15923852 | 0.73 | MAPT (0.44) | KDM4EALDH1A1HPGDMAPTFABP4 | |
| SCHEMBL10029426 | 0.73 | ALDH1A1 (0.33) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL17532970 | 0.71 | ALDH1A1 (0.32) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL7760842 | 0.71 | ALDH1A1 (0.33) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL1918395 | 0.71 | ALDH1A1 (0.40) | ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL12852210 | 0.69 | KDM4E (0.32) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646876-B | Method for preparing polyesteramide through organic catalysis | 南京工业大学 | 2018-06-19 | — | — | CN | disclosed |
| EP-2392606-B1 | PREPARATION METHOD OF POLYLACTIC ACID BY CATALYSIS OF CARBENE DERIVATIVES | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2018-03-28 | — | — | EP | disclosed |
| US-9040653-B2 | Ring-opening polymerization of cyclic compounds catalyzed by carbene derivatives | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2015-05-26 | — | — | US | disclosed |
| US-9029497-B2 | Method of making polylactic acid using carbene derivatives as the catalyst | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2015-05-12 | — | — | US | disclosed |
| EP-2327736-B1 | METHOD OF ADJUSTABLE AND CONTROLLABLE RING-OPENING POLYMERIZATION OF CYCLIC COMPOUNDS BY CATALYSIS OF CARBENE DERIVATIVES | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2015-03-18 | — | — | EP | disclosed |
| US-20110152493-A1 | METHOD OF MAKING POLYLACTIC ACID USING CARBENE DERIVATIVES AS THE CATALYST | NANJING UNIVERSITY OF TECHNOLOGY | 2011-06-23 | — | — | US | disclosed |
| US-20110144296-A1 | RING-OPENING POLYMERIZATION OF CYCLIC COMPOUNDS CATALYZED BY CARBENE DERIVATIVES | NANJING UNIVERSITY OF TECHNOLOGY | 2011-06-16 | — | — | US | disclosed |
| EP-2327736-A1 | METHOD OF ADJUSTABLE AND CONTROLLABLE RING-OPENING POLYMERIZATION OF CYCLIC COMPOUNDS BY CATALYSIS OF CARBENE DERIVATIVES | Nanjing University of Technology (CN) | 2011-06-01 | — | — | EP | disclosed |