SCHEMBL17576293

SCHEMBL17576293

Cc1ccccc1N1C=CN(c2ccccc2)[C@H]1C

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.36
▸ LMNA P02545 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ MGLL Q99685 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ ELANE P08246 1/20 0.35
▸ ADRB1 P08588 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ MAPT P10636 4/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ AR P10275 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15396987 1.00 ALDH1A1 (0.36) ALDH1A1LMNAHTTMGLLHPGD
SCHEMBL19230062 1.00 ALDH1A1 (0.36) ALDH1A1LMNAHTTMGLLHPGD
SCHEMBL19725777 0.90 ALDH1A1 (0.42) ALDH1A1LMNAMGLLHPGDSMN1; SMN2
SCHEMBL16769703 0.85 MAOA (0.33) ALDH1A1HPGD
SCHEMBL21074257 0.84 MAPT (0.36) ALDH1A1LMNAHTTMGLLHPGD
SCHEMBL19999689 0.84 MAPT (0.36) ALDH1A1LMNAHTTMGLLHPGD
SCHEMBL12170156 0.84 MAOA (0.41) ALDH1A1LMNAMGLLHPGDSMN1; SMN2
SCHEMBL24547836 0.81 ALDH1A1 (0.34) ALDH1A1LMNASMN1; SMN2TDP1TSHR
SCHEMBL22781115 0.81 ALDH1A1 (0.36) ALDH1A1LMNAHTTMGLLHPGD
SCHEMBL21074256 0.81 MAPT (0.37) ALDH1A1LMNAMGLLHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11716898-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 — — US disclosed
US-11716898-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 — — US disclosed
US-20220213116-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-07-07 — — US disclosed
US-20220194956-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-06-23 — — US disclosed
US-20200295276-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORP (US) 2020-09-17 — — US disclosed
US-10707427-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-07-07 — — US disclosed
US-10418569-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-17 — — US disclosed
US-10276805-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-04-30 — — US disclosed
US-10256419-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-04-09 — — US disclosed
US-20180090691-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-03-29 — — US disclosed
US-9911928-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-03-06 — — US disclosed
US-9911928-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-03-06 — — US disclosed
US-20170237018-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2017-08-17 — — US disclosed
US-20170237018-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2017-08-17 — — US disclosed
US-20170155064-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2017-06-01 — — US disclosed
US-20160276603-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-09-22 — — US disclosed
US-20160218303-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-07-28 — — US disclosed
US-20160218303-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-07-28 — — US disclosed
US-20160072082-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-03-10 — — US disclosed
US-20160072082-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-03-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160276603-A1 Organic Electroluminescent Materials and Devices EML4, BICRA, TBCB ALDH1A1 889/4885LMNA 1835/4885HTT 2986/4885
US-20170237018-A1 Organic Electroluminescent Materials and Devices OCIAD2, OCIAD1, JUND ALDH1A1 2423/4885LMNA 3502/4885HTT 973/4885
US-20180090691-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, TYR, CPNE4 ALDH1A1 2007/4885LMNA 2569/4885HTT 1073/4885
US-20220194956-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF PIEZO1, LEF1, TMEM109 ALDH1A1 119/4885LMNA 1524/4885HTT 3527/4885
US-10276805-B2 Organic electroluminescent materials and devices EML4, TYR, CPNE4 ALDH1A1 2007/4885LMNA 2569/4885HTT 1073/4885
US-20220213116-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF PIEZO1, LEF1, TMEM109 ALDH1A1 129/4885LMNA 1322/4885HTT 3696/4885
US-11716898-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND ALDH1A1 2423/4885LMNA 3502/4885HTT 973/4885
US-10707427-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND ALDH1A1 2262/4885LMNA 2414/4885HTT 1215/4885
US-10418569-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP2 ALDH1A1 1620/4885LMNA 2707/4885HTT 2766/4885
US-20200295276-A1 Organic Electroluminescent Materials and Devices OCIAD2, OCIAD1, JUND ALDH1A1 2423/4885LMNA 3502/4885HTT 973/4885
US-10256419-B2 Organic electroluminescent materials and devices EML4, TYR, CPNE4 ALDH1A1 2007/4885LMNA 2569/4885HTT 1073/4885
US-20160218303-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP2 ALDH1A1 1620/4885LMNA 2707/4885HTT 2766/4885
US-20160072082-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, TYR, CPNE4 ALDH1A1 2007/4885LMNA 2569/4885HTT 1073/4885
US-20170155064-A1 Organic Electroluminescent Materials and Devices OCIAD2, OCIAD1, JUND ALDH1A1 1651/4885LMNA 3896/4885HTT 622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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