SCHEMBL19170201

SCHEMBL19170201

CCCCN1CCN(Cc2ccccc2)CCN(Cc2ccccc2)CCN(Cc2ccccc2)CC1

nearest known ligand 0.71

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 1/20 0.69
SIGMAR1 Q99720 4/20 0.67
MC4R P32245 1/20 0.67
LMNA P02545 1/20 0.59
POLB P06746 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13632432 1.00 CCR3 (0.69) CCR3SIGMAR1MC4RLMNAPOLB
SCHEMBL6740759 1.00 CCR3 (0.69) CCR3SIGMAR1MC4RLMNAPOLB
SCHEMBL1244038 0.95 CCR3 (0.72) CCR3SIGMAR1MC4RLMNAPOLB
SCHEMBL12040820 0.93 CCR3 (0.70) CCR3SIGMAR1MC4RLMNAPOLB
SCHEMBL8723260 0.93 CCR3 (0.70) CCR3SIGMAR1MC4RLMNAPOLB
SCHEMBL15800706 0.93 CCR3 (0.70) CCR3SIGMAR1MC4RLMNAPOLB
SCHEMBL8097472 0.89 SIGMAR1 (0.72) CCR3SIGMAR1MC4RLMNAPOLB
SCHEMBL6744977 0.89 SIGMAR1 (0.72) CCR3SIGMAR1MC4RLMNAPOLB
SCHEMBL19169973 0.89 SIGMAR1 (0.72) CCR3SIGMAR1MC4R
SCHEMBL12040822 0.89 CCR3 (0.64) CCR3SIGMAR1MC4RLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170210714-A1 MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2017-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170210714-A1 MACROCYCLIC COMPLEXES, THEIR PROCESS OF PREPARATION AND USE AS PET IMAGING AGENTS MPI, PAICS, TFEB CCR3 432/4885SIGMAR1 2616/4885MC4R 213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.