Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.72 |
| ▸ | MC4R | P32245 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CCR3 | P51677 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097472 | 1.00 | SIGMAR1 (0.72) | SIGMAR1MC4RLMNAPOLBCCR3 | |
| SCHEMBL6740759 | 0.89 | CCR3 (0.69) | SIGMAR1MC4RLMNAPOLBCCR3 | |
| SCHEMBL13632432 | 0.89 | CCR3 (0.69) | SIGMAR1MC4RLMNAPOLBCCR3 | |
| SCHEMBL19170201 | 0.89 | CCR3 (0.69) | SIGMAR1MC4RLMNAPOLBCCR3 | |
| SCHEMBL6659339 | 0.87 | SIGMAR1 (0.86) | SIGMAR1MC4RLMNAPOLBCCR3 | |
| SCHEMBL1244038 | 0.87 | CCR3 (0.72) | SIGMAR1MC4RLMNAPOLBCCR3 | |
| SCHEMBL8723260 | 0.85 | CCR3 (0.70) | SIGMAR1MC4RLMNAPOLBCCR3 | |
| SCHEMBL15800706 | 0.85 | CCR3 (0.70) | SIGMAR1MC4RLMNAPOLBCCR3 | |
| SCHEMBL12040820 | 0.85 | CCR3 (0.70) | SIGMAR1MC4RLMNAPOLBCCR3 | |
| SCHEMBL1415730 | 0.85 | SIGMAR1 (1.00) | SIGMAR1MC4RLMNAPOLBCCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689919-B1 | SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-02-10 | — | — | US | disclosed |