Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379389 | 0.95 | — | — | |
| SCHEMBL20317552 | 0.86 | CES2 (0.50) | TDP1CES2ALDH1A1TSHRPLA2G4B | |
| SCHEMBL28334432 | 0.85 | TDP1 (0.59) | TDP1CES2HSD17B10ALDH1A1TSHR | |
| SCHEMBL14403358 | 0.84 | TDP1 (0.39) | TDP1CES2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL22856291 | 0.84 | CES2 (0.52) | TDP1CES2ALDH1A1TSHRTHRB | |
| SCHEMBL8390457 | 0.84 | TDP1 (0.39) | TDP1CES2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL7243144 | 0.84 | MEN1 (0.50) | TDP1CES2ALDH1A1TSHRMEN1 | |
| SCHEMBL15315156 | 0.84 | CES2 (0.38) | CES2HSD17B10ALDH1A1TSHRPLA2G4B | |
| SCHEMBL20317554 | 0.84 | TDP1 (0.39) | TDP1CES2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL13025474 | 0.84 | MEN1 (0.40) | TSHRMEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017125933-A1 | FORMATION OF FUNCTIONALIZED NANOPARTICLES BY SUPRAMOLECULAR CO-ASSEMBLY | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-07-27 | — | — | WO | disclosed |