Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15223141 | 0.95 | — | — | |
| SCHEMBL19170656 | 0.84 | TDP1 (0.41) | MEN1KMT2ATSHRTHRBHTT | |
| SCHEMBL29997828 | 0.83 | MEN1 (0.47) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL20317554 | 0.82 | TDP1 (0.39) | TSHRALDH1A1TDP1CES2CYP3A4 | |
| SCHEMBL14403358 | 0.82 | TDP1 (0.39) | TSHRALDH1A1TDP1CES2CYP3A4 | |
| SCHEMBL22856291 | 0.82 | CES2 (0.52) | TSHRTHRBALDH1A1TDP1CES2 | |
| SCHEMBL8390457 | 0.82 | TDP1 (0.39) | TSHRALDH1A1TDP1CES2CYP3A4 | |
| SCHEMBL10072103 | 0.81 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL25290891 | 0.80 | CES2 (0.45) | MEN1KMT2ATSHRTHRBHTT | |
| SCHEMBL16421150 | 0.80 | TDP1 (0.38) | TSHRALDH1A1TDP1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620771-B2 | Extreme pressure additives for lubricating compositions (e.g., greases) | R. T. VANDERBILT COMPANY, INC. | 2003-09-16 | — | — | US | disclosed |
| US-20020058594-A1 | Thiadiazole dimer additives and lubricating compositions containing the same | R.T. VANDERBILT COMPANY, INC. (US) | 2002-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058594-A1 | Thiadiazole dimer additives and lubricating compositions containing the same | RAD51, TPR, LIG1 | MEN1 4395/4885KMT2A 3668/4885TSHR 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.