Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 8/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25029532 | 0.92 | MEN1 (0.44) | MEN1KMT2AGLP1RTSHRRECQL | |
| SCHEMBL13024328 | 0.90 | CASP2 (0.42) | MEN1KMT2AGLP1RTSHRRECQL | |
| SCHEMBL13024334 | 0.90 | ALDH1A1 (0.40) | MEN1KMT2AEPHX2GLP1RTSHR | |
| SCHEMBL13025473 | 0.89 | MEN1 (0.39) | MEN1KMT2AGLP1RTSHRRECQL | |
| SCHEMBL13024335 | 0.89 | MEN1 (0.39) | MEN1KMT2AGLP1RTSHRRECQL | |
| SCHEMBL13024561 | 0.89 | MEN1 (0.39) | MEN1KMT2AGLP1RTSHRRECQL | |
| SCHEMBL21106543 | 0.88 | MEN1 (0.47) | MEN1KMT2AGLP1RTSHRRECQL | |
| SCHEMBL13684294 | 0.87 | ALDH1A1 (0.40) | MEN1KMT2AEPHX2TSHRRECQL | |
| SCHEMBL23696405 | 0.87 | CASP2 (0.44) | MEN1KMT2AGLP1R | |
| SCHEMBL19277702 | 0.87 | CASP2 (0.44) | MEN1KMT2AGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317057-A1 | SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES | NOVO NORDISK A/S (DK) | 2010-12-16 | — | — | US | disclosed |