Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19173239 | 0.83 | MEN1 (0.97) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL19173838 | 0.76 | EPHX2 (0.56) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL21606698 | 0.75 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL19173837 | 0.74 | SIGMAR1 (0.58) | ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL29649691 | 0.71 | MEN1 (0.54) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL21606691 | 0.70 | KDM4E (0.50) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6714503 | 0.70 | TAAR1 (0.75) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL19362954 | 0.68 | SRD5A2 (0.47) | MEN1KMT2AHIF1A | |
| SCHEMBL21765281 | 0.67 | EPHX2 (0.33) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2748297 | 0.66 | MEN1 (0.51) | MEN1KMT2AALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017127306-A1 | ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTION | ARISAN THERAPEUTICS (US) | 2017-07-27 | — | — | WO | disclosed |