Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21752926 | 0.84 | MEN1 (0.46) | EPHX2KDM4CMEN1KMT2AALDH1A1 | |
| SCHEMBL21765346 | 0.78 | EPHX2 (0.39) | EPHX2MEN1KMT2AGAAMAPT | |
| SCHEMBL21606698 | 0.78 | ALDH1A1 (0.51) | EPHX2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL21765283 | 0.77 | KDM4C (0.33) | EPHX2KDM4CCTSDBACE1BACE2 | |
| SCHEMBL19362954 | 0.73 | SRD5A2 (0.47) | EPHX2MEN1KMT2AGAAMAPT | |
| SCHEMBL20482167 | 0.68 | RXRA (0.49) | EPHX2KDM4CALDH1A1L3MBTL1 | |
| SCHEMBL19362915 | 0.68 | HPGD (0.50) | EPHX2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL21628479 | 0.67 | PARP10 (0.58) | KMT2AALDH1A1 | |
| SCHEMBL19173263 | 0.67 | MEN1 (0.68) | ALOX5APMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL21606691 | 0.67 | KDM4E (0.50) | ALOX5APMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039094-A1 | PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERATIVE ACTIVITY | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |