Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 13/20 | 0.45 |
| ▸ | PKD1 | P98161 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19174100 | 0.83 | MAP3K14 (0.44) | MAP3K14PKD1SCN9A | |
| SCHEMBL19174039 | 0.82 | MAP3K14 (0.49) | MAP3K14PKD1SCN9AGRM5 | |
| SCHEMBL19173576 | 0.79 | MAP3K14 (0.46) | MAP3K14PKD1 | |
| SCHEMBL16505657 | 0.77 | MAP3K14 (0.77) | MAP3K14PKD1 | |
| SCHEMBL16522771 | 0.75 | MAP3K14 (0.63) | MAP3K14PKD1 | |
| SCHEMBL19173916 | 0.74 | MAP3K14 (0.41) | MAP3K14 | |
| SCHEMBL19173854 | 0.71 | MAP3K14 (0.42) | MAP3K14PKD1 | |
| SCHEMBL23870034 | 0.71 | MAP3K14 (0.37) | MAP3K14GRM5 | |
| SCHEMBL22744185 | 0.71 | MAP3K14 (0.37) | MAP3K14GRM5 | |
| SCHEMBL22744160 | 0.71 | GRM5 (0.35) | MAP3K14GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170210724-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | GENENTECH, INC. (US) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210724-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | NFKB2, NFKB1, NFKBIA | MAP3K14 553/4885PKD1 2437/4885SCN9A 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.