Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 13/20 | 0.44 |
| ▸ | PKD1 | P98161 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19173883 | 0.83 | MAP3K14 (0.45) | MAP3K14PKD1SCN9A | |
| SCHEMBL19173576 | 0.80 | MAP3K14 (0.46) | MAP3K14PKD1 | |
| SCHEMBL16505970 | 0.80 | MAP3K14 (0.72) | MAP3K14PKD1 | |
| SCHEMBL19173898 | 0.79 | MAP3K14 (0.49) | MAP3K14PKD1 | |
| SCHEMBL19174039 | 0.79 | MAP3K14 (0.49) | MAP3K14PKD1SCN9A | |
| SCHEMBL16522768 | 0.78 | MAP3K14 (0.61) | MAP3K14PKD1 | |
| SCHEMBL19173916 | 0.75 | MAP3K14 (0.41) | MAP3K14 | |
| SCHEMBL23870034 | 0.71 | MAP3K14 (0.37) | MAP3K14 | |
| SCHEMBL22744185 | 0.71 | MAP3K14 (0.37) | MAP3K14 | |
| SCHEMBL19173854 | 0.70 | MAP3K14 (0.42) | MAP3K14PKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170210724-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | GENENTECH, INC. (US) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210724-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | NFKB2, NFKB1, NFKBIA | MAP3K14 553/4885PKD1 2437/4885SCN9A 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.