Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23168692 | 1.00 | GRIN1 (0.40) | GRIN1GRIN2ABRD4BRD2EHMT2 | |
| SCHEMBL16179443 | 0.86 | — | — | |
| SCHEMBL16532437 | 0.86 | — | — | |
| SCHEMBL16478702 | 0.86 | — | — | |
| SCHEMBL761946 | 0.77 | GRIN1 (0.42) | GRIN1GRIN2ABRD4BRD2EHMT2 | |
| SCHEMBL9197159 | 0.74 | GRIN1 (0.40) | GRIN1GRIN2ABRD4BRD2EHMT2 | |
| SCHEMBL23794163 | 0.74 | GRIN1 (0.37) | GRIN1GRIN2ABRD4BRD2EHMT2 | |
| SCHEMBL23869801 | 0.74 | GRIN1 (0.37) | GRIN1GRIN2ABRD4BRD2EHMT2 | |
| SCHEMBL23869808 | 0.74 | GRIN1 (0.37) | GRIN1GRIN2ABRD4BRD2EHMT2 | |
| SCHEMBL23794083 | 0.74 | GRIN1 (0.37) | GRIN1GRIN2ABRD4BRD2EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170210724-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | GENENTECH, INC. (US) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210724-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | NFKB2, NFKB1, NFKBIA | GRIN1 1319/4885GRIN2A 2033/4885BRD4 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.