Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | USP7 | Q93009 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYBB | P04839 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286970 | 0.85 | TNKS2 (0.58) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL6124127 | 0.78 | KMT2A (0.52) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL27704231 | 0.77 | USP7 (0.48) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL17538667 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL18314788 | 0.74 | KMT2A (0.59) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL27767134 | 0.73 | USP7 (0.47) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL27603678 | 0.73 | GAPDH (0.57) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL13834469 | 0.72 | KMT2A (0.68) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL28837986 | 0.72 | TNKS2 (0.66) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL9539830 | 0.72 | BRD4 (0.52) | MEN1KMT2AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017127627-A1 | COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2017-07-27 | — | — | WO | disclosed |