Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 7/20 | 0.48 |
| ▸ | PYGM | P11217 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518214 | 0.87 | BCHE (0.52) | TK1BCHE | |
| SCHEMBL24516961 | 0.87 | BCHE (0.52) | TK1BCHE | |
| SCHEMBL4786342 | 0.83 | TK1 (0.49) | TK1PYGMP2RY6P2RY14BCHE | |
| SCHEMBL5898590 | 0.82 | TK1 (0.62) | TK1PYGM | |
| SCHEMBL14231186 | 0.82 | TK1 (0.62) | TK1PYGM | |
| SCHEMBL2043148 | 0.82 | TK1 (0.62) | TK1PYGM | |
| SCHEMBL4438998 | 0.80 | TK1 (0.47) | TK1PYGMP2RY6P2RY14BCHE | |
| SCHEMBL4438991 | 0.80 | TK1 (0.47) | TK1PYGMP2RY6P2RY14BCHE | |
| SCHEMBL13968218 | 0.80 | TK1 (0.46) | TK1PYGMP2RY6P2RY14BCHE | |
| SCHEMBL12914128 | 0.79 | SLC28A1 (0.43) | P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844430-B2 | DNA sequencing reaction additive | QIAGEN SCIENCES, LLC (US) | 2020-11-24 | — | — | US | disclosed |
| US-20190226018-A1 | SEQUENCING ADDITIVE | IsoPlexis Corporation | 2019-07-25 | — | — | US | disclosed |
| US-20170211134-A1 | THIOL-CONTAINING CLEAVE REAGENTS AND OXIDATIVE WASH | IsoPlexis Corporation | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844430-B2 | DNA sequencing reaction additive | RNGTT, NSUN2, NT5C3B | TK1 143/4885PYGM 4054/4885P2RY6 906/4885 |
| US-20190226018-A1 | SEQUENCING ADDITIVE | NT5C3B, RNGTT, NSUN2 | TK1 143/4885PYGM 4067/4885P2RY6 793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.