Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.43 |
| ▸ | CPN1 | P15169 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19178114 | 1.00 | CPB2 (0.43) | CPB2CPN1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL8871986 | 0.86 | CPN1 (0.50) | CPB2CPN1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL19815424 | 0.84 | CPN1 (0.46) | CPB2CPN1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL19815425 | 0.84 | CPN1 (0.46) | CPB2CPN1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL15203782 | 0.84 | CPN1 (0.48) | CPB2CPN1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL5515416 | 0.83 | SMN1; SMN2 (0.54) | CPB2CPN1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL18050479 | 0.83 | SMN1; SMN2 (0.54) | CPB2CPN1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL1188893 | 0.82 | CPN1 (0.47) | CPB2CPN1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL6135596 | 0.82 | CPN1 (0.47) | CPB2CPN1LTA4HSLC1A3SLC1A2 | |
| SCHEMBL7382758 | 0.80 | CA2 (0.53) | LTA4HSLC1A3SLC1A2SLC1A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376427-B1 | CRYSTALLINE FORMS OF A 3-CARBOXYPROPYL-AMINOTETRALIN COMPOUND | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2017-08-02 | — | — | EP | disclosed |