Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28979080 | 0.78 | GRM6 (0.42) | GRM6POLBSIGMAR1S1PR1S1PR5 | |
| SCHEMBL25195472 | 0.78 | GRM6 (0.49) | GRM6POLBSIGMAR1MAPTS1PR1 | |
| SCHEMBL1834264 | 0.76 | ACHE (0.49) | MC4RSIGMAR1MAPT | |
| SCHEMBL11476458 | 0.75 | SIGMAR1 (0.51) | GRM6MC4RSIGMAR1MAPTS1PR1 | |
| SCHEMBL25154331 | 0.75 | CHRM1 (0.42) | POLBSIGMAR1MAPT | |
| SCHEMBL25154443 | 0.75 | CHRM1 (0.42) | POLBSIGMAR1MAPT | |
| SCHEMBL25154711 | 0.75 | CHRM1 (0.42) | POLBSIGMAR1MAPT | |
| SCHEMBL25154567 | 0.75 | CHRM1 (0.42) | POLBSIGMAR1MAPT | |
| SCHEMBL25154579 | 0.75 | CHRM1 (0.42) | POLBSIGMAR1MAPT | |
| SCHEMBL25154702 | 0.75 | CHRM1 (0.42) | POLBSIGMAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040653-B2 | Ring-opening polymerization of cyclic compounds catalyzed by carbene derivatives | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2015-05-26 | — | — | US | disclosed |
| EP-2327736-B1 | METHOD OF ADJUSTABLE AND CONTROLLABLE RING-OPENING POLYMERIZATION OF CYCLIC COMPOUNDS BY CATALYSIS OF CARBENE DERIVATIVES | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2015-03-18 | — | — | EP | disclosed |
| US-20110144296-A1 | RING-OPENING POLYMERIZATION OF CYCLIC COMPOUNDS CATALYZED BY CARBENE DERIVATIVES | NANJING UNIVERSITY OF TECHNOLOGY | 2011-06-16 | — | — | US | disclosed |
| EP-2327736-A1 | METHOD OF ADJUSTABLE AND CONTROLLABLE RING-OPENING POLYMERIZATION OF CYCLIC COMPOUNDS BY CATALYSIS OF CARBENE DERIVATIVES | Nanjing University of Technology (CN) | 2011-06-01 | — | — | EP | disclosed |