Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1917883 | 0.78 | GRM6 (0.43) | GRM6S1PR5S1PR1POLBSIGMAR1 | |
| SCHEMBL25195472 | 0.75 | GRM6 (0.49) | GRM6S1PR5S1PR1GBA1TP53 | |
| SCHEMBL28112011 | 0.72 | ACHE (0.39) | CA1CA2CA4CA9 | |
| SCHEMBL27840206 | 0.72 | SIGMAR1 (0.47) | GBA1TP53MDM2SIGMAR1CYP2C19 | |
| SCHEMBL28126702 | 0.71 | TP53 (0.41) | CA1CA2CA4CA9TP53 | |
| SCHEMBL8409861 | 0.71 | AGTR2 (0.61) | GRM6S1PR5S1PR1AGTR2SIGMAR1 | |
| SCHEMBL2864891 | 0.71 | AGTR2 (0.61) | GRM6S1PR5S1PR1AGTR2SIGMAR1 | |
| SCHEMBL8343227 | 0.71 | AGTR2 (0.61) | GRM6S1PR5S1PR1AGTR2SIGMAR1 | |
| SCHEMBL8408488 | 0.70 | GBA1 (0.48) | GBA1POLBSIGMAR1CYP2D6CYP2C9 | |
| SCHEMBL28845589 | 0.70 | GBA1 (0.48) | GRM6S1PR5S1PR1GBA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110475765-B | Preparation method of amide compound | 广荣化学株式会社 | 2023-04-07 | — | — | CN | disclosed |
| CN-110475765-A | The preparation method of amides compound | KOEI CHEMICAL CO | 2019-11-19 | — | — | CN | disclosed |