SCHEMBL1918

SCHEMBL1918

O=[C]c1ccc(Cl)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2323033 0.92 CYP1A2 (0.48)
SCHEMBL11510990 0.85 MAOA (0.52)
SCHEMBL8772462 0.85 TAAR1 (0.48)
SCHEMBL8772582 0.83 SRD5A2 (0.59)
SCHEMBL104811 0.83 APP (0.32)
SCHEMBL22721374 0.80 HTR2A (0.43)
SCHEMBL2037119 0.77 MAOB (0.62)
SCHEMBL2347410 0.75 CYP2A6 (0.50)
SCHEMBL3149415 0.73 MMP3 (0.38)
1,4-Dichlorobenzene SCHEMBL8161191 0.73 LMNA (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9535 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
EP-3929207-B1 PEPTIDE FTTFTVT FOR USE IN TREATING FIBROSIS UNIV TEXAS (US) 2024-07-17 EP claimed
CN-118271331-A Gelsemin derivatives, synthesis method and application thereof in inhibiting tumor cell proliferation 赣江中药创新中心 2024-07-02 CN claimed
WO-2024127026-A1 MEMBRANE FILTRATION-ASSISTED SOLUTION PHASE OLIGONUCLEOTIDE SYNTHESIS Exactmer Limited (GB) 2024-06-20 WO claimed
CN-118164997-A Sesquiterpene lactone scaberol C thioether derivative, and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118164996-A Sesquiterpene lactone scaberol C selenoether derivative, preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118164998-A Sesquiterpene lactone scaberol C dithio carbamate derivative and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
EP-3684780-B1 FLOXURIDINE SYNTHESIS NuCana plc (GB) 2024-05-29 EP claimed
CN-117945876-A Benzophenone compound and preparation method and application thereof 湖北理工学院 2024-04-30 CN claimed
US-4018932-A 2,3,5,6-TETRAHYDRO-IMIDAZO (2,1-6) THIAZOLE AMERICAN CYANAMID COMPANY (US) 1977-04-19 US claimed
US-4003875-A ULTRAVIOLET ABSORBERS CIBA-GEIGY CORPORATION (US) 1977-01-18 US claimed
US-3998807-A ARABINOFURANOSYL CYTOSINES AND METHODS OF MAKING SYNTEX (U.S.A.) INC. (US) 1976-12-21 US claimed
US-3988326-A Process for N-acylation of 7 amino cephem compounds MEIJI SEIKA KAISHA, LTD. (JA) 1976-10-26 US claimed
US-3987026-A POLYESTERS CIBA-GEIGY CORPORATION (US) 1976-10-19 US claimed
US-3975532-A ANALGESIC ICI UNITED STATES INC. (US) 1976-08-17 US claimed
US-3953596-A 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals ICI UNITED STATES INC. (US) 1976-04-27 US claimed
US-3951964-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-04-20 US claimed
US-3943132-A Process for the preparation of hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed
US-3933827-A CYTOSTATIC AGENTS HOFFMANN-LA ROCHE INC. (US) 1976-01-20 US claimed