Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 12/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19181982 | 0.74 | TLR7 (0.40) | TLR7TLR8LMNAALDH1A1MAPT | |
| SCHEMBL19204368 | 0.72 | TLR7 (0.36) | TLR7TLR8ALDH1A1MAPTAPLNR | |
| SCHEMBL19181987 | 0.69 | ALDH1A1 (0.36) | TLR7TLR8ALDH1A1MAPT | |
| SCHEMBL17557157 | 0.67 | TLR7 (0.65) | TLR7TLR8 | |
| SCHEMBL1302206 | 0.64 | TLR7 (0.49) | TLR7TLR8LMNAALDH1A1MAPT | |
| SCHEMBL1301770 | 0.63 | TLR7 (0.46) | TLR7TLR8LMNAALDH1A1MAPT | |
| SCHEMBL128 | 0.60 | TLR7 (0.49) | TLR7TLR8 | |
| SCHEMBL1302080 | 0.60 | TLR7 (0.44) | TLR7LMNAALDH1A1SMN1; SMN2 | |
| Tetrabuthylammonium SCHEMBL9062848 | 0.58 | TSHR (0.65) | LMNAALDH1A1 | |
| SCHEMBL14758128 | 0.58 | TLR7 (0.51) | TLR7TLR8ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220289744-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-09-15 | — | — | US | disclosed |
| US-11279701-B2 | Immunomodulators and immunomodulator conjugates | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-03-22 | — | — | US | disclosed |
| US-20200325136-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2020-10-15 | — | — | US | disclosed |
| US-10730871-B2 | Immunomodulators and immunomodulator conjugates | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2020-08-04 | — | — | US | disclosed |
| US-20170217960-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730871-B2 | Immunomodulators and immunomodulator conjugates | CD40, CD47, FCGRT | TLR7 124/4885TLR8 184/4885LMNA 4880/4885 |
| US-20220289744-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | CD47, IL2, ICOS | TLR7 65/4885TLR8 58/4885LMNA 4877/4885 |
| US-11279701-B2 | Immunomodulators and immunomodulator conjugates | IL2, CD47, FCGRT | TLR7 44/4885TLR8 99/4885LMNA 4878/4885 |
| US-20170217960-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | CD47, CD40, HLA-DRB1 | TLR7 115/4885TLR8 150/4885LMNA 4879/4885 |
| US-20200325136-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | IL2, CD47, FCGRT | TLR7 44/4885TLR8 99/4885LMNA 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.