SCHEMBL19181986

SCHEMBL19181986

O=CC1(C=O)C=CC=C(c2ccccc2)C1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.32
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28658397 0.84 HDAC1 (0.33) NPC1RAB9AALDH1A1LMNAHPGD
SCHEMBL28540735 0.79 NPC1 (0.32) NPC1RAB9AALDH1A1LMNAHPGD
SCHEMBL28513177 0.79 NPC1 (0.32) NPC1RAB9AALDH1A1LMNAHPGD
SCHEMBL30163529 0.79 NPC1 (0.32) NPC1RAB9AALDH1A1LMNAHPGD
SCHEMBL29283410 0.77 HDAC4 (0.31) NPC1RAB9A
SCHEMBL4939750 0.76 NPC1 (0.33) NPC1RAB9AALDH1A1LMNAHPGD
SCHEMBL27711885 0.76
SCHEMBL8957775 0.76 HDAC1 (0.37) NPC1RAB9AALDH1A1LMNAHPGD
Methane SCHEMBL28875106 0.74 HDAC1 (0.36) NPC1RAB9AALDH1A1LMNAHPGD
SCHEMBL9006818 0.74 THRB (0.35) NPC1RAB9AALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111116528-B Method for producing aromatic primary diamine 罗地亚经营管理公司 2023-08-01 CN disclosed
US-11066377-B2 Process for producing aromatic primary diamines RHODIA OPERATIONS (FR) 2021-07-20 US disclosed
CN-112978709-A Carbon quantum dot precursor composition, carbon quantum dot and preparation method thereof 中国科学院大连化学物理研究所 2021-06-18 CN disclosed
CN-112334795-A Liquid composition, quantum dot-containing film, optical film, light-emitting display element panel, and light-emitting display device 东京应化工业株式会社 2021-02-05 CN disclosed
US-10899726-B2 Process for producing aromatic primary diamines RHODIA OPERATIONS (FR) 2021-01-26 US disclosed
CN-106575080-B Energy-sensitive resin composition 东京应化工业株式会社 2020-08-11 CN disclosed
EP-3674285-A1 PROCESS FOR PRODUCING M-XYLYLENEDIAMINE RHODIA OPERATIONS (FR) 2020-07-01 EP disclosed
US-20200172501-A1 PROCESS FOR PRODUCING AROMATIC PRIMARY DIAMINES SPECIALTY OPERATIONS FRANCE (FR) 2020-06-04 US disclosed
CN-111116528-A Process for producing aromatic primary diamines 罗地亚经营管理公司 2020-05-08 CN disclosed
EP-3166921-B1 PROCESS FOR PRODUCING AROMATIC PRIMARY DIAMINES RHODIA OPERATIONS (FR) 2020-02-19 EP disclosed
CN-106488905-B Process for producing aromatic primary diamines 罗地亚经营管理公司 2019-12-17 CN disclosed
CN-105579907-B Radiation-sensitive composition and pattern production method 东京应化工业株式会社 2019-12-17 CN disclosed
WO-2018045142-A1 IMMUNE CHECKPOINT INHIBITORS, COMPOSITIONS AND METHODS THEREOF POLARIS PHARMACEUTICALS, INC. (US) 2018-03-08 WO disclosed
US-20170217916-A1 PROCESS FOR PRODUCING AROMATIC PRIMARY DIAMINES SPECIALTY OPERATIONS FRANCE (FR) 2017-08-03 US disclosed
CN-105579907-A Radiation-sensitive composition and pattern production method TOKYO OHKA KOGYO CO LTD 2016-05-11 CN disclosed