Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4002907 | 0.87 | LMNA (0.33) | THRBTDP1HDAC1HDAC2HDAC4 | |
| SCHEMBL6849682 | 0.85 | CYP3A4 (0.31) | TDP1ALDH1A1 | |
| SCHEMBL4619747 | 0.81 | HDAC4 (0.33) | THRBTDP1HDAC1HDAC2HDAC4 | |
| SCHEMBL8957775 | 0.78 | HDAC1 (0.37) | HDAC1HDAC2NPC1RAB9AALDH1A1 | |
| SCHEMBL29007685 | 0.78 | HDAC4 (0.32) | THRBTDP1HDAC4NPC1RAB9A | |
| SCHEMBL28926102 | 0.78 | HDAC4 (0.32) | THRBTDP1HDAC4NPC1RAB9A | |
| Methane SCHEMBL28875106 | 0.77 | HDAC1 (0.36) | HDAC1HDAC2NPC1RAB9AALDH1A1 | |
| SCHEMBL28658397 | 0.76 | HDAC1 (0.33) | HDAC1HDAC2NPC1RAB9AALDH1A1 | |
| SCHEMBL27668644 | 0.76 | HDAC4 (0.31) | HDAC4NPC1RAB9ALMNA | |
| SCHEMBL29283410 | 0.76 | HDAC4 (0.31) | HDAC4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090184-C | Heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-04 | — | — | CN | disclosed |
| CN-1046714-C | Diaryl oxazole derivative and its preparation method, application and pharmaceutical composition | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-11-24 | — | — | CN | disclosed |
| CN-1229795-A | Heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-09-29 | — | — | CN | disclosed |
| CN-1138328-A | Heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0736018-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |