Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18539083 | 0.93 | ALDH1A1 (0.42) | ALDH1A1MAPTTSHRGAAL3MBTL1 | |
| SCHEMBL18499282 | 0.88 | ALDH1A1 (0.39) | ALDH1A1MAPTTSHRGAAL3MBTL1 | |
| SCHEMBL4960125 | 0.85 | LMNA (0.45) | ALDH1A1MAPTTSHRL3MBTL1NPSR1 | |
| SCHEMBL19679637 | 0.84 | TSHR (0.44) | ALDH1A1MAPTTSHRGAANPSR1 | |
| SCHEMBL465384 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP2D6 | |
| SCHEMBL16217699 | 0.80 | SLC1A3 (0.36) | ALDH1A1MAPTTSHRCYP2D6SLC1A3 | |
| SCHEMBL19184702 | 0.80 | ALDH1A1 (0.34) | ALDH1A1MAPTTRPM8TSHRCYP2D6 | |
| SCHEMBL16217705 | 0.79 | CASP1 (0.35) | ALDH1A1MAPTTSHRL3MBTL1CYP2D6 | |
| SCHEMBL13080336 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TSHRCYP2D6 | |
| SCHEMBL79588 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MAPTTSHRGAACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718989-B1 | Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes | SIRRUS, INC. (US) | 2017-08-01 | — | — | US | disclosed |
| US-9718989-B1 | Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes | SIRRUS, INC. (US) | 2017-08-01 | — | — | US | disclosed |