Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL802755 | 0.91 | POLB (0.45) | POLBAPEX1HTTTDP1KDM4E | |
| SCHEMBL18472703 | 0.88 | THRB (0.48) | POLBAPEX1HTTTDP1KDM4E | |
| SCHEMBL803176 | 0.88 | POLB (0.43) | POLBAPEX1HTTTDP1KDM4E | |
| SCHEMBL19156765 | 0.87 | POLB (0.42) | POLBAPEX1HTTTDP1KDM4E | |
| SCHEMBL18432719 | 0.87 | KDM4E (0.52) | POLBAPEX1HTTTDP1KDM4E | |
| SCHEMBL18517314 | 0.86 | POLB (0.41) | POLBAPEX1HTTTDP1KDM4E | |
| SCHEMBL12321292 | 0.86 | LMNA (0.42) | POLBAPEX1HTTTDP1KDM4E | |
| SCHEMBL22426054 | 0.86 | POLB (0.42) | POLBAPEX1HTTTDP1KDM4E | |
| SCHEMBL19413811 | 0.85 | POLB (0.46) | POLBAPEX1HTTTDP1KDM4E | |
| SCHEMBL15433974 | 0.85 | THRB (0.46) | POLBAPEX1HTTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9719016-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2017-08-01 | — | — | US | disclosed |